A man with a history of depression and anxiety who had suffered an overdose of Viagra has lost consciousness.
On Tuesday, the US Food and Drug Administration (FDA) issued a warning to men with a history of depression and anxiety who had been prescribed a low dose of the drug, but not the medication.
The FDA is warning consumers that a new drug containing the antidepressant selective serotonin reuptake inhibitor (SSRI) sertraline might increase the risk of a man’s heart attack and stroke, according to an FDA statement.
The drug, which is sold under the brand name Zoloft, is known as a “molecular-targeted drug” that is designed to treat depression and anxiety. It is also used to treat other psychiatric disorders.
In this story, we will be providing information about the antidepressant drug sertraline, as well as the other two SSRIs.
This article will focus on sertraline, its possible uses, risks and side effects.
This article was last updated at 6:00 p.m. PT on April 24th, 2025.
This article was first published at 6:00 p.m.
The FDA issued a warning to consumers last week after they were prescribed a low dose of the drug. The FDA said that “these side effects may be dose related.”
Sertraline is a selective serotonin reuptake inhibitor (SSRI), which means it increases the levels of serotonin in the brain and can have a negative impact on blood pressure and heart rate.
The drug is not recommended for use by pregnant women or women who are planning to become pregnant because of risk of heart problems, or by anyone who has a history of depression or anxiety.
Sertraline may be prescribed to individuals who are experiencing symptoms of depression or other mental health disorders, such as anxiety disorders or depression with a genetic component, to treat these conditions.
If you have a history of depression or other mental health disorders, like generalized anxiety disorder, you should not take sertraline. If you have taken antidepressants for a long time, it is not recommended that you try them and the effects may be too strong. Sertraline is not recommended for use by women or children because of potential risk of birth defects or other health problems.
Sertraline can cause side effects, although they are typically short-term and temporary. Common long-term side effects of SSRIs include headache, nausea, insomnia, diarrhea, dizziness, and constipation.
Some people may experience depression or anxiety during sertraline treatment. However, it is not known whether the depression or anxiety can be treated with sertraline.
According to the FDA, the side effects of SSRIs are usually mild, with most side effects affecting around the mouth, but the most common side effects for sertraline include headache, nausea, diarrhea, and dizziness.
Sertraline is only approved by the FDA for the treatment of depression and anxiety disorders. But the drug can also be used to treat other mental health conditions, like schizophrenia.
Sertraline is only approved for use by adults 18 years of age or older, but a small number of people may not be suitable. The FDA also notes that some patients have an increased risk of stroke, heart attack or blood clots.
The FDA warns that it is not clear how many people are currently taking SSRIs to treat depression and anxiety, as well as other mental health conditions, and may not consider sertraline for treatment of these conditions if it is not prescribed for such conditions.
Sertraline may also be used off label to treat other mental health conditions, including dementia and anxiety.
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